ACTIVITIES - 吉森研究室 | 大阪大学大学院生命機能研究科細胞内膜動態研究室／医学系研究科遺伝学教室

NEWS: 当研究室の田端桂介さんの論文がNature Communicationsに掲載されました

原著論文

Tabata K, Imai K, Fukuda K, Yamamoto K, Kunugi H, Fujita T, Kaminishi T, Tischer C, Neumann B, Reither S, Verissimo F, Pepperkok R, Yoshimori T, Hamasaki M.

Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy
Nat Commun. (2024) Aug 21;15(1):7194. doi: 10.1038/s41467-024-51402-w.

PubMed

Yanagawa K, Kuma A, Hamasaki M, Kita S, Yamamuro T, Nishino K, Nakamura S, Omori H, Kaminishi T, Oikawa S, Kato Y, Edahiro R, Kawagoe R, Taniguchi T, Tanaka Y, Shima T, Tabata K, Iwatani M, Bekku N, Hanayama R, Okada Y, Akimoto T, Kosako H, Takahashi A, Shimomura I, Sakata Y, Yoshimori T.

The Rubicon-WIPI axis regulates exosome biogenesis during ageing
Nat Cell Biol. (2024) Sep;26(9):1558-1570. Epub 2024 Aug 22.
doi: 10.1038/s41556-024-01481-0.

PubMed

Kitta S, Kaminishi T, Higashi M, Shima T, Nishino K, Nakamura N, Kosako H, Yoshimori T, Kuma A.

YIPF3 and YIPF4 regulate autophagic turnover of the Golgi apparatus.
EMBO J. (2024) Jul;43(14):2954-2978. Epub 2024 May 31.
doi: 10.1038/s44318-024-00131-3

PubMed

Cui M, Yamano K, Yamamoto K, Yamamoto-Imoto H, Minami S, Yamamoto T, Matsui S, Kaminishi T, Shima T, Ogura M, Tsuchiya M, Nishino K, Layden BT, Kato H, Ogawa H, Oki S, Okada Y, Isaka Y, Kosako H, Matsuda N, Yoshimori T, Nakamura S.

HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence.

Proc Natl Acad Sci U S A. 121: e2306454120 (2024) doi: 10.1073/pnas.2306454120.

PubMed

Kakuda K, Ikenaka K, Kuma A, Doi J, Aguirre C, Wang N, Ajiki T, Choong CJ, Kimura Y, Badawy SMM, Shima T, Nakamura S, Baba K, Nagano S, Nagai Y, Yoshimori T, Mochizuki H.

Lysophagy protects against propagation of α-synuclein aggregation through ruptured lysosomal vesicles.

Proc Natl Acad Sci U S A. 121: e2312306120 (2023) doi: 10.1073/pnas.2312306120.

Pubmed

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原著論文

Tabata K, Imai K, Fukuda K, Yamamoto K, Kunugi H, Fujita T, Kaminishi T, Tischer C, Neumann B, Reither S, Verissimo F, Pepperkok R, Yoshimori T, Hamasaki M.

Yanagawa K, Kuma A, Hamasaki M, Kita S, Yamamuro T, Nishino K, Nakamura S, Omori H, Kaminishi T, Oikawa S, Kato Y, Edahiro R, Kawagoe R, Taniguchi T, Tanaka Y, Shima T, Tabata K, Iwatani M, Bekku N, Hanayama R, Okada Y, Akimoto T, Kosako H, Takahashi A, Shimomura I, Sakata Y, Yoshimori T.

Kitta S, Kaminishi T, Higashi M, Shima T, Nishino K, Nakamura N, Kosako H, Yoshimori T*, Kuma A*.

Cui M, Yamano K, Yamamoto K, Yamamoto-Imoto H, Minami S, Yamamoto T, Matsui S, Kaminishi T, Shima T, Ogura M, Tsuchiya M, Nishino K, Layden BT, Kato H, Ogawa H, Oki S, Okada Y, Isaka Y, Kosako H, Matsuda N, Yoshimori T, Nakamura S.

Kakuda K, Ikenaka K, Kuma A, Doi J, Aguirre C, Wang N, Ajiki T, Choong CJ, Kimura Y, Badawy SMM, Shima T, Nakamura S, Baba K, Nagano S, Nagai Y, Yoshimori T, Mochizuki H.

Kitta S, Kaminishi T, Higashi M, Shima T, Nishino K, Nakamura N, Kosako H, Yoshimori T, Kuma A.