吉森研究室
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中村さんらの研究成果がNature Communicationsに掲載

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原著論文

Unno R, Kawabata T, Taguchi K, Sugino T, Hamamoto S, Ando R, Okada A, Kohri K, Yoshimori T, Yasui T.

Deregulated MTOR (mechanistic target of rapamycin kinase) is responsible for autophagy defects exacerbating kidney stone development.
Autophagy, 1-15. [Epub ahead of print] doi: 10.1080/15548627.2019.1635382.

Lystad AH*, Carlsson SR*, de la Ballina LR, Kauffman KJ, Nag S, Yoshimori T, Melia TJ, Simonsen A*.

Distinct functions of ATG16L1 isoforms in membrane binding and LC3B lipidation in autophagy-related processes.
Nat. Cell Biol., 21(3), 372-383 (2019) Epub 2019 Feb 18. doi: 10.1038/s41556-019-0274-9

Nakamura S#, Oba M#, Suzuki M, Takahashi A, Yamamuro T, Fujiwara M, Ikenaka K, Minami S, Tabata N, Yamamoto K, Kubo S, Tokumura A, Akamatsu K, Miyazaki Y, Kawabata T, Hamasaki M, Fukui K, Sango K, Watanabe Y, Takabatake Y, Kitajima TS, Okada Y, Mochizuki H, Isaka Y, Antebi A, Yoshimori T*.

Suppression of autophagic activity by Rubicon is a signature of aging.
Nat. Commun., 10(1), 847 (2019) Epub 2019 Feb 19. doi: 10.1038/s41467-019-08729-6.

Chang C, Young LN, Morris KL, von Bülow S, Schöneberg J, Yamamoto-Imoto H, Oe Y, Yamamoto K, Nakamura S, Stjepanovic G, Hummer G, Yoshimori T, Hurley JH*.

Bidirectional Control of Autophagy by BECN1 BARA Domain Dynamics.
Mol Cell. 73(2), 339-353.e6 (2019) Epub 2018 Dec 20. doi: 10.1016/j.molcel.2018.10.035.

Tan JM, Mellouk N, Osborne SE, Ammendolia DA, Dyer DN, Li R, Brunen D, van Rijn JM, Huang J, Czuczman MA, Cemma MA, Won AM, Yip CM, Xavier RJ, MacDuff DA, Reggiori F, Debnath J, Yoshimori T, Kim PK, Fairn GD, Coyaud E, Raught B, Muise AM, Higgins DE, Brumell JH*.

An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread.
Nat Microbiol. 3(12), 1472–1485 (2018) Epub 2018 Nov 26. doi: 10.1038/s41564-018-0293-5.

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