吉森研究室
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当研究室の橘田真理さんの論文がThe EMBO Journalに掲載されました

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原著論文

Kitta S, Kaminishi T, Higashi M, Shima T, Nishino K, Nakamura N, Kosako H, Yoshimori T*, Kuma A*.

YIPF3 and YIPF4 regulate autophagic turnover of the Golgi apparatus.
EMBO J. (2024) doi: 10.1038/s44318-024-00131-3

PubMed

Cui M, Yamano K, Yamamoto K, Yamamoto-Imoto H, Minami S, Yamamoto T, Matsui S, Kaminishi T, Shima T, Ogura M, Tsuchiya M, Nishino K, Layden BT, Kato H, Ogawa H, Oki S, Okada Y, Isaka Y, Kosako H, Matsuda N, Yoshimori T, Nakamura S.

HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence.

Proc Natl Acad Sci U S A. 121: e2306454120 (2024) doi: 10.1073/pnas.2306454120.

PubMed

Kakuda K, Ikenaka K, Kuma A, Doi J, Aguirre C, Wang N, Ajiki T, Choong CJ, Kimura Y, Badawy SMM, Shima T, Nakamura S, Baba K, Nagano S, Nagai Y, Yoshimori T, Mochizuki H.

 Lysophagy protects against propagation of α-synuclein aggregation through ruptured lysosomal vesicles.

Proc Natl Acad Sci U S A. 121: e2312306120 (2023) doi: 10.1073/pnas.2312306120.

Pubmed

Shima T, Ogura M, Matsuda R, Nakamura S, Jin N, Yoshimori T, Kuma A.

The TMEM192-mKeima probe specifically assays lysophagy and reveals its initial steps. J Cell Biol. 222: e202204048 (2023) doi: 10.1083/jcb.202204048.

PubMed

Ogura M, Kaminishi T, Shima T, Torigata M, Bekku N, Tabata K, Minami S, Nishino K, Nezu A,  Hamasaki M,  Kosako H,  Yoshimori T,  Nakamura S.

Microautophagy regulated by STK38 and GABARAPs is essential to repair lysosomes and prevent aging.

EMBO Rep. 24 :e57300 (2023) . doi: 10.15252/embr.202357300.

PubMed

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