吉森研究室
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山室さんらの研究成果がPLoS Geneticsに掲載

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原著論文

Yamamuro T, Kawabata T, Fukuhara A, Saita S, Nakamura S, Takeshita H, Fujiwara M, Enokidani Y, Yoshida G, Tabata K, Hamasaki M, Kuma A, Yamamoto K, Shimomura I, Yoshimori T

Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. Nat. Commun., 11(1):4150. (2020) Epub 2020 Aug 18. doi: 10.1038/s41467-020-17985-w.

Murase D, Kusaka-Kikushima A, Hachiya A, Fullenkamp R, Stepp A, Imai A, Ueno M, Kawabata K, Takahashi Y, Hase T, Ohuchi A, Nakamura S, Yoshimori T

Autophagy Declines with Premature Skin Aging resulting in Dynamic Alterations in Skin Pigmentation and Epidermal Dierentiation. Int J Mol Sci., 21(16):5708. 2020 Aug 9. doi: 10.3390/ijms21165708

Aoyama S, Nishida Y, Fujitani Y, Fukunaka A, Miyatsuka T, Suzuki L, Himuro M, Yoshimori T, Watada H

Rubicon in pancreatic beta cells plays a limited role in maintaining glucose homeostasis following increased insulin resistance., Endocr J., 2020 Jul 16. doi: 10.1507/endocrj.EJ20-0326

Bhargava HK, Tabata K, Byck JM, Hamasaki M, Farrell DP, Anishchenko I, DiMaio F, Im YJ, Yoshimori T, Hurley JH

Structural Basis for Autophagy Inhibition by the Human Rubicon-Rab7 Complex.

Proc Natl Acad Sci U S A, 117(29):17003-17010 (2020), Epub 2020 Jul 6. doi: 10.1073/pnas.2008030117

 

Yamamoto YH, Kasai A, Omori H, Takino T, Sugihara M, Umemoto T, Hamasaki M, Hatta T, Natsume T, Morimoto RI, Arai R, Waguri S, Sato M, Sato K, Bar-Nun S, Yoshimori T, Noda T, Nagata K.

ERdj8 governs the size of autophagosomes during the formation process.
J Cell Biol., 219(8):e201903127.(2020). doi: 10.1083/jcb.201903127.

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© 2018 T.YOSHIMORI LAB.

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